Originally Posted by DavidHC

It's really difficult to say for sure whether supplements work, which ones do and how much is needed. The precision is lacking because of lack of funding and controlled studies. So you have yourself as the test subject. I usually giver it at least a week, possibly two or even longer to see if a new supplement works. I use different brands, always focusing on the purest ingredients with fewest additives and fillers. I use Doctor's Best Benfotiamine, 300 twice a day, and use a number of products from Pure Encapsulations, which though more expensive is pure and uses quality ingredients. I also take vitamin C, B12 and folate, and D and a few others. MrsD., and other will likely chime in too.

Soon I'll add Acety L- Carnitine like Pinkynose and look forward to trying it.

good luck!