Dr. Coimbra is a superlative practitioner of medicine in the western tradition. An MD, Phd... In the months since I have discovered the work of Dr. Coimbra, I have yet to come across credible assertions that he is a quack, or that his protocol is ineffective, quite the contrary... My take-a-way from all that I have read, Coimbra, et al, is that Vit. D3 is, at least, a VERY important adjunct to standard treatments for autoimmune diseases, and possibly, at very high doses a monotherapy capable of producing outcomes that exceed those of standard therapies. I suggest that all inform themselves as to the safety, and efficacy of Vit. D3 in treating AI diseases. I hope all realize that their physicians must be consulted/informed before making any additions/adjustments to their treatments... patrick