Most reactions to IVIG are rate related...meaning the infusion was too fast. As soon as you feel slightest headache, you should tell nurse and they should slow down the rate of infusion. Even after receiving IVIG on/off (mostly on) for 19 years, the infusion still starts out very slow and gradually increases as I tolerate it. Everyone is different and they probably did start it slow. You just may need it even slower at first.

There is also a difference in products. I have had more reactions with different brands (which have different concentrations). You may need a lower concentration. Roughly how long did your infusion take?

I just hate to see you give up after one infusion. Yes, those headaches are bad!! But it may just mean you need slower rate, different product with lower concentration or different pre-meds (I use Tylenol, Benadryl and IV steroids). But like I said, the amount you're getting won't likely help much with neuropathy...too small amount. So while you have the opportunity to try this due to IgG levels, might as welll find the right combination/product for you...just in case you can get approved for proper amount down the road.