The only change would be to properly address the immune deficiency...with IVIG. Then you might have more success with the Methotrexate and Humira. It would help stop the infections, so you can continue treatment cycles better.

There is a new option you may want to consider for the gastroparesis...Mestinon. it is used for Myasthenia Gravis, but it has been found to help autonomic dysfunction....including GI motility issues. The Mayo Clinic discusses it on the website for increasing BP in those with autonomic neuroapthy, but it can also help GI issues. Worth talking to your doctor about it as an option. You can google Mestinon for gastroparesis and get numerous articles to read.

I tried it, but had a bad side-effect...caused me to have asthma attack after each dose.

Hope this helps.