well said I think billbobby21, for me at least.....but I cant find a doc across the US that knows the ins and outs of L-Methionine and 5HTP........in my limited experience an individual must figure this pharmacological conundrum out on their own (or with help from folk like yourself) in order to properly implement the L-Methionine/5HTP etc......I would get a look from my doc at least like....."who the hell are you and what do you know of pharmacology/o-chem/biosynthesis pathways" like for example the Krebs Cycle.......ask your doc how many NADH's it takes to make one ATP.......he has no clue.......until he googles (if your lucky)......."the role of NADH in the production of adenosine tri phosphate as a product of the citric acid cycle"............they don't remember/know............you need a seriously savvy doc....not neuro......not specialized enough......at the least a movement disorder specialist as part of a team working in tandem with Psychoanalysts, Primary Care, neuro, and homeopath/nutritionist...........most of us cant put together a competent team like that god knows ive tried from Colorado to Alaska........I wish you luck hangon and advise that you study the pharmokinetics of amino acid chains and how to best "interject" this info. into your regime. just my .25 cents worth......a year or more study time for the patient/caregiver.........of course I may be underrating the tenacity/knowledge base of the layman/laywoman...........and plead ignorance to the extent at which hangon is into pharmokinetics/pharmodynamics. If your well versed in such subjects than PD Alchemy is not unjustified in this situation.......research/implement/observe/adjust.......tell your quack.....sorry ...."doc".....what you are going to do and why and let the ducks fight it out amongst themselves as they look for loopholes in the Hippocratic oath.....which is taking on the appearance of swiss cheese....baby swiss.....lots of holes! at our expense.....Literally......

(don't crucify me hehehehe)

peace,
BP