Thanks for the post on your Rx experience. My husband had a family member go that way and while it really did save her life in the beginning, it seemed to be less effective over time, no matter how many times she switched meds. My husband never went that direction but has tried many "natural" means with little help. He tried the amino therapy approach a few years ago and started to see some positive effect but the nausea was too much and interfered with his job. But now that nothing else has worked, we started talking about researching the nausea issue to see if he could give it another go with that method again. So glad I found this board and thank you for the recommendation for Dr Chad. Correct me if I'm wrong, but when I was reading about Dr. Hintz several years back didn't he pursue this line of research because of his own battle with Bipolar? We do our best research when it's personal!