Thanks MrsD and en_block!
I will take into consideration those risks.
en_block, can you do the weekly test yourself at home ?

I'm getting Rituximab and it is helping a lot, the problem is that I can take it only in 6 months interval, while its effect lasting only 2-3 months, so this year has been a roller coaster...
The neuro said the effect is cumulative, so gradually it might get longer.
The rheum suggested the plaquenil to help the fatigue in the meantime, so I'm considering giving it a chance. It is challenging (impossible?) to return to work when 6-8months a year it is difficult to get out of bed and my brain is on a strike.

My SFN and POTS are probably caused by autoimmune disease, if plaquenil is considered a disease modifier drug, can it help with the SFN, POTS?