View Single Post
Old 11-08-2016, 01:54 AM
johnt johnt is offline
Senior Member
 
Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,059
15 yr Member
johnt johnt is offline
Senior Member
 
Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,059
15 yr Member
Default

Wendy,

You write:
"I walk a very fine line between not enough so I have freezing until the next dose kicks in, or taking enough so I don't freeze but end up with dyskinesia. My MDS told me a couple of years ago that he could help me with the freezing or the dyskinesia but not both."

Have you tried reducing the time between doses? Your first dose of the day would be unchanged, the subsequent doses, because they come earlier and, therefore, have a higher starting point, may need to be lower. You may need to fit another dose in. In this way you might be able to have a net increase in your daily levodopa dose without increasing your CMAX, thus decreasing "off" time, while avoiding dyskinesia.

I'm also 11 years after diagnosis and get up in the morning feeling fairly good, sometimes going hours without taking my meds. I too put this down to some continued endogenous dopamine production and storage.

John
__________________
Born 1955. Diagnosed PD 2005.
Meds 2010-Nov 2016: Stalevo(75 mg) x 4, ropinirole xl 16 mg, rasagiline 1 mg
Current meds: Stalevo(75 mg) x 5, ropinirole xl 8 mg, rasagiline 1 mg
johnt is offline   Reply With QuoteReply With Quote