I had MRI's and they didn't show any type of atrophy...yet the muscle biopsy did. I don't think MRI is capable of seeing all types of atrophy.

The muscle biopsy wasn't a big deal. yes, it is invasive, but healed quickly and had no lasting problems (unlike the the nerve biopsy and permanent sensory loss).

I had signs of muscle wasting in my legs...that is why he did the muscle biopsy. They already wanted to do the nerve biopsy due to neuropathy and numbness. It didn't dictate any particular treatment, but added information to the bigger picture...confirming the wide spread neuropathy.