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Old 12-02-2016, 03:25 AM
johnt johnt is offline
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Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,059
15 yr Member
johnt johnt is offline
Senior Member
 
Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,059
15 yr Member
Default Gut microbiota linked to PD, again

In a paper published yesterday, Sampson et al. write [1]:

"Our findings establish that the microbiota are required for the hallmark motor and GI dysfunction in a mouse model of PD, via postnatal gut-brain signaling by microbial molecules that impact neuroinflammation and αSyn aggregation. Coupled with emerging research that has linked gut bacteria to disorders such as anxiety, depression, and autism, we propose the provocative hypothesis that certain neurologic conditions that have classically been studied as disorders of the brain may also have etiologies in the gut."

They raise the possibility that correcting dysbiosis may slow the progression of PD.

It seems to me that a sensible reaction of PwP to these findings is to measure the impact of live fermented foods on their PD symptoms.

Reference

[1] "Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease"
Sampson et al.
Cell, Dec 2016
http://www.cell.com/cell/fulltext/S0092-8674(16)31590-2

John
__________________
Born 1955. Diagnosed PD 2005.
Meds 2010-Nov 2016: Stalevo(75 mg) x 4, ropinirole xl 16 mg, rasagiline 1 mg
Current meds: Stalevo(75 mg) x 5, ropinirole xl 8 mg, rasagiline 1 mg
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