Dan, my reading of the evidence is that rasagiline blocks what is called the intrinsic pathway of apoptosis, mainly through preventing the release of cytochrome c from mitochondria.

This evidence, valuable as it is, has come mainly from cell culture and animal models.

I think that we will need to learn a lot more about this before we can extrapolate with any confidence about what might happen to a person who decides to discontinue rasagiline taken as treatment for PD.