I take 800mg total. I take 700 at night, and I take the other 100 in the morning. I have to take some in the morning because it helps with my OCD and anxiety symptoms, but that 100mg is all I can tolerate at baseline. I have been on much higher doses during the day when I was manic, but I was so high they were not sedating at all.

I have built up a tolerance for Seroquel at this point, but between it and all the other meds I take, it has to be contributing to my fatigue.

I think it is sedating for everyone, at least initially. A lot of people stop taking it before they build up any tolerance for that reason.

When I worked at the VA, they prescribed small doses of Seroquel off label for patients as a sleep aide, but many of them were psych patients anyway.