Hey, Robt111. Most pain that gets better throughout the day has an inflammatory cause, such as arthritis. It might be worthwhile to consult with a rheumatologist, or talk to an internist about it. Pain can also be a sign of cancer.

Is your mattress older? That may contribute to any pain if it is!

Pain can be a result of weak muscles. But that would normally improve when muscles become stronger. Pain is a part of MG, but only if muscles are weaker or there is atrophy due to a sedentary life. Anyone who has weak muscles can have pain, cramping, spasming, etc. Patients with MS experience that as well. Athletes do as well, but it happens after intense activity, such as marathons.

Since many of us have other autoimmune diseases, it's worthwhile talking to a doctor about other mitigating factors (even thyroid disease, celiac disease, B12 and D deficiencies, etc.).

I hope you can find some relief!

Annie