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Old 02-28-2017, 11:53 AM
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
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15 yr Member
mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Wink

There is no upper limit set by our government on B12.

I would not stop your supplements at the levels you state. Most of us here at PN keep our B12 at 1000 and above from blood serum.

You really need to discontinue supplements several days before any testing to get accurate results. Otherwise, there may be false elevations. Injections should be 7 days old or so. Oral at least 3 to 5 days.

If you have not been tested for MTHFR DNA mutations, you will not know if injectable cyanocobalamin will work for you. B12 is easiest, most effectively, and affordable to take orally in the form of methylcobalamin. Taken daily ON AN EMPTY STOMACH can give good results and is easier on the body. A large bolus of injection is cleared in 72 hrs, and the rest of the month or longer there is none being provided. Oral use provides daily amounts for the body to send to the needy areas that use it. The liver, bone marrow, muscles, and brain are huge consumers of B12.... but really all tissues need it on a regular basis.

Cyanocobalamin is synthetic and requires activation in the body to its active forms. Methylcobalamin is the main active form that the tissues use. If a person has the MTHFR mutation, this cannot occur so cyano form is useless. Up to 40% of people are thought today to have one or more mutations in this system.

More info here:
MTHFR Mutation | MTHFR Gene Mutation | What is MTHFR? - MTHFR.net

This is my B12 thread. On it are links to studies and medical sites explaining further:
STICKY - The Vitamin B12 Thread:
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