Hi faith,
I've not used Inositol myself although I've seriously thought about trying it as I have panic attacks although they seem to come in bouts.
There have been a number of studies done on the use of Inositol in various conditions. It appears to me that it is more beneficial for Panic Disorder than for other things. e.g. OCD. I did find one study suggesting it was beneficial for OCD but I haven't seen that replicated in other ones. Maybe I missed some.
Inositol is something I most probably would have used to help my son with his anxiety when he was younger if I'd known about it. (He's 20 now) The fact that it appears to have a very good side-effects profile is also very good.
http://www.ncbi.nlm.nih.gov/sites/en...=pubmed_docsum
J Clin Psychopharmacol. 2001 Jun;21(3):335-9.
Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder.
Palatnik A, Frolov K, Fux M, Benjamin J.
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Only 70% of patients respond to current treatments for panic disorder, and many discontinue drugs because of side effects. myo-Inositol, a natural isomer of glucose and a precursor for the second-messenger phosphatidyl-inositol system, has previously been found superior to placebo in the treatment of depression, panic disorder, and obsessive-compulsive disorder (OCD), but a direct comparison with an established drug has never been performed. A double-blind, controlled, random-order crossover study was undertaken to compare the effect of inositol with that of fluvoxamine in panic disorder. Twenty patients completed 1 month of inositol up to 18 g/day and 1 month of fluvoxamine up to 150 mg/day. Improvements on Hamilton Rating Scale for Anxiety scores, agoraphobia scores, and Clinical Global Impressions Scale scores were similar for both treatments. In the first month, inositol reduced the number of panic attacks per week (mean and SD) by 4.0 (2) compared with a reduction of 2.4 (2) with fluvoxamine (p = 0.049). Nausea and tiredness were more common with fluvoxamine (p = 0.02 and p = 0.01, respectively). Because inositol is a natural compound with few known side effects, it is attractive to patients who are ambivalent about taking psychiatric medication. Continuing reports of inositol's efficacy in the treatment of depression, panic disorder, and OCD should stimulate replication studies.
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http://www.ncbi.nlm.nih.gov/sites/en...=pubmed_docsum
Int J Neuropsychopharmacol. 1999 Sep;2(3):193-195.
Inositol versus placebo augmentation of serotonin reuptake inhibitors in the treatment of obsessive-compulsive disorder: a double-blind cross-over study.
Fux M, Benjamin J, Belmaker RH.
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Current serotonin reuptake inhibitor (SRI) treatments for obsessive-compulsive disorder (OCD) provide only partial benefit. A previous study suggested that inositol alone is efficacious in OCD. Ten DSM-IV OCD patients completed a study of 18 g inositol or placebo for 6 wk each in addition to ongoing SRI treatment in a double-blind randomized cross-over design. Weekly assessments included the Yale-Brown Obsessive-Compulsive Scale (YBOCS) and Hamilton Depression and Anxiety scales. No significant difference was found between the two treatment phases
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