ashleyk said: "This should apply to PD as well."

I think this is a leap too far.

From the 1st link: " ... these results strongly indicate that inhibition of [calcineurin] ... may protect neurons from the damaging effects of amyloid-beta
oligomers."

This, for me, is the essence of the paper. No mention is made of alpha-synuclein, and no mention is made of PD.

From the 2nd link: "When a cell becomes overloaded with alpha-synuclein, calcium surges into the cytoplasm and binds the protein calmodulin, which then activates calcineurin. The phosphatase plucks phosphates from dozens of different proteins."

I can understand that inhibiting calcineurin could very well limit the damaging effects of toxic forms of alpha-synuclein. However, a more direct approach would be to target alpha-synuclein itself, an approach which has been adopted by many other research efforts.