I'm sorry about your mother-in-law, Donna. This must be a very difficult time for your husband. I can understand why it would be hard to know what's appropriate to do regarding the birthday party, but you have very good judgement.

Seroquel is definitely sedating, but many people can get used to it over time. 25mg isn't a big dose. I hope he can build up a tolerance for it soon, but if it seems like the sedation isn't getting better in a week to ten days, you should contact his doctor because it's probably not the right med for him.