Nan, I don't think it can be narrowed down yet. N equals 2 at present. I think that N needs to equal at least 18 (i.e. the end of the current trial) before any narrowing down takes place.

Regarding the possibility of a compassionate response, I see loads of obstacles to overcome:
- determining who qualifies;
- setting the length of the response;
- getting permission from donors for their plasma to be used in this way;
- setting up the infrastructure, and processes, to support this response;
- securing the funding.

I'm not sure that a young-plasma service for PwPs is even the goal of this research. Maybe if the current trials are successful, the next project will be to find out exactly which component of young plasma is responsible for the improvement(s). Maybe it will only be made available to PwPs if/when it reaches the form of a medication/supplement.