It seems you are as determined with your research efforts as I am in refusal to accept this garbage diagnosis. I am convinced there is a metabolic error which won't allow me to absorb nutrients -some of which are copper, iron, and iodine. I know it's genetic, and we have the EDS diagnosis, but I don't believe that it's that simple. I don't think I have defective collagen and connective tissue. I think it's a metabolic mutation.