The main thing that worked for me was the desensitization over time. Water in particular is supposed to really help. I agree about the constant pressure clothing vs. flowy. Mine is in my foot/leg. If I wear leggings it doesn't bother my lower leg as much as floppy sweats do because the fabric isn't bumping my leg all the time.
The other thing for me has been the trial and error and eventually finding a good combo of meds that work for me to bring all of it down a few notches.