Hi Kirsty

Welcome to NeuroTalk.

I am in remission from Major Depressive Disorder. When I was not in remission I experienced some of the things that you have described. I do not have any signs of ganglionopathy or similar.

I was on an anti-depressant for some years. After a while I decided to discontinue, with approval and monitoring from my psychiatrist. This was uneventful.

Another option which you could consider is seeing a clinical psychologist with experience of using Cognitive Behavioural Therapy (CBT) with his/her clients. CBT takes time and practise to learn but there is good evidence that it can be highly effective for people with Major Depressive Disorder and other mood disorders.

Using CBT methods, which my clinical psychologist taught me, has been invaluable in my staying in remission.

All the best.