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Member
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Join Date: Jun 2015
Location: Austin, Texas
Posts: 112
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Member
Join Date: Jun 2015
Location: Austin, Texas
Posts: 112
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Levodopa is the active ingredient.
Carbidopa is a buffer to help prevent nausea (too much Levodopa triggers the brain into thinking the stomach has nausea, but it is all in the brain).
Hence 25/100 is common Carbidopa/Levodopa ratio. You can find 10/100 C/L formulations, but more often people have nausea issues.
Cabidopa by itself is available as a separate medication. USA trade name is Lydosyn. Often as 25mg, taken in addition with 25/100 Sinemet
Comtan just helps the levodopa stick around longer. So if C/L starts to wear off after four hours, your doc may add Comtan to see if C/L benefits last six hours.
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Born 1958. Diagnosed PD 2014.
Meds Sept 2016: 5x daily: 2 - Sinemet 25/100 + 200mg Comtan; 50/200 ER Sinement (bedtime).
Oct 2016 - DBS - bilateral GPi (PD & Dystonia). Still a work in progress. (Reduced meds to 4 - 25/100 & 50/200 ER Bedtime daily; but need six months to see how DBS/Meds play out)
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