Quote:
Originally Posted by HangOn
Dr Chad has him on dosages spaced at three times a day, mealtimes, so his schedule is as follows:
Up at 5:30, 1st supps at 6:00, next at 12 noon, tests at 4:30, and last dosage at 6:30pm, bed at 9:30.
He is to take 1 NR just at B and D and then spread the D5 between the three mealtimes. I believe he is due for another test soon with the dopamine challenge results.
He's used to the routine, doesn't find it difficult to follow, likes the results so far, but is hoping it will increase some more. Any thoughts?
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That schedule looks pretty good to me.
Now since he has been having nausea while on 12 D5 Mucuna pills a day, Dr. Oler will start changing the NR dosage to try to eliminate the nausea side effect. He will go through the dosing values of 2-1-3-4-8 of NR, and it is likely that one of those dosages will alleviate the nausea. If they don't then he will go through 5-6-7 of NR, then start adding in RE if the nausea is still present after all those dosages. You basically have to try to figure out what the needed amount of 5-htp is for side effect alleviation.
If the dopamine value that was seen on the test where he was on 12 D5 pills a day was over 40,000, then he will also start adding in Tyrosine powder in 1 TBSP increments to eliminate dopamine fluctuations resulting from melanin steal. Getting the fluctuations taken care of will actually be done before adjusting the NR dosing if they are present. You can ask Dr. Oler if they are present in your next consult, as the test results they give to patients only say critical high which means over 20k but not necessarily over 40k.
After you get the fluctuations taken care of, if they are present, and the side effects taken care of, by adjusting the 5-htp dosing, he will then start increasing the D5 Mucuna dosing by 6 or 8 pill cycles every 7 days, then do a pill stop after each dosing. He is currently at 12 pills a day, so he would increase to 18 pills for 7 days, then do a pill stop, where you quit taking all the D5 pills for 2-3 days which decreases the amount in the body to values representing intake between the 12-18 pills that was jumped over. This ensures the needed dosing value isn't missed as intake of too little or too much L-dopa will result in the same symptoms.
Once the side effects and possibly fluctuations are taken care of, it should be a relatively quick process. Finding the optimal D5 dosing usually only takes 1-3 months, depending on how much the individual needs.