Yes I was on vicadin but off of it for 2 weeks and tramadol. There is no narcotics or pain killer use at the cleveland clinic so I had to go off. I'm not a med person at all. I always get other side effects but at the same time need some relief when doing more. I have been prescribed too naproxen I think and motrin 600. I'm trying not to take any so just pushing to the limit where I don't need but sometimes even at rest I do. I just know with the anti depressent for pain relief it takes awhile, a combo of meds,or a super dose. I can't imagine with the troubles I seem to have with meds. They sure as hell don't make me feel less depressed. Now or even in the past when I used them for that. I felt worse in that department. I must be a real nut that they don't even help. Hey at least I admit it. Just kidding.