I have been taking mucuna for year and a half on daily bases. It helped me to cut down from taking 3x100/25 LC daily to 2x100/25 LC with addition of mucuna. My dosage and timing of taking LC and mucuna if very flexible depending if I am home or going out, what I eat, stress level, etc. I still work full time in the office from 8 to 4:30 Monday to Friday, five years after diagnosis. On working days I usually take 100/25 LC at 6:30am and 1 capsule of Dopa Mucuna at 7:20 with some cooked oatmeal and coffee (no protein). If I take only LC in the morning without mucuna, I am off in 2.5 hours or less: addition of mucuna extends my on time up to 4.5 hours. At 11:00 am I take half of 100/25 LC and 1 Dopa Mucuna capsule together and go for lunch at 12:00 (again I try to avoid protein). I take another half of 100/25 LC and 1 Dopa Mucuna around 3:00 pm and this is it for the day. But, if I have meeting at work for exempla at 2:00 I will take 1tsp of Zandopa mucuna powder mix in water half an hour earlier to maintain my on time and not to have to take meds while I am at the meeting (nobody at work knows that I have PD) . Also, stress will shorten my on time considerably, or cancel meds all together, so on a stressful morning I might take extra 1 tsp of Zandopa at 9:30 am. If I am going out in the evening I will increase my mucuna intake usually by taking 1tsp Zandopa 1-2 hr after I take half of the 100/25 LC with 1 Dopa Mucuna capsule. I try Banyan mucuna organic powder but it doesn’t work for me as well as Zandopa. On the weekends I take meds and mucuna on as needed bases trying to take less LC if I can. When I am taking LC with mucuna I have better and more dependable relive of my symptoms (tremor, stiffness, rigidity, drugging left foot, etc”). Increasing LC intake before I added mucuna really made me feel tired; I was falling asleep sitting at my desk. Mucuna doesn't seem to do that. I guess everyone has their own unique reaction to meds or mucuna. I think that the most important thing is to listen to your body and also when trying mucuna to find the brand and the dosage that works for you.