SPM Active is made by a company called Metagenics though it is also available from various on-line shops. It contains two fatty acids, 18-hydroxy-eicosapentaenoic acid (18-HEPE) and 17-hydroxy-docosahexaenoic acid (17-HDHA) which Metagenics sources from oily fish. There is limited clinical evidence that both of these have anti-inflammatory properties.

I don't know if 18-HEPE and 17-HDHA are available as prescription drugs. This could be worth checking out - if so, that could be cheaper than buying them from commercial sources.