First off hello everyone. Longtime lurker. Just registered.

I have really sever PN in my feet only.

Recently got a compounded RX filled but and scare of some of the ingredients. I don't know any of the percentages in each medicine as it is not listed.

Ingredients are as follows:

Ketamine
Amitriptyline
Bupivacaine
Clonidine
Gabapentin

Ketamine worries the worst as it is derived from PCP and is a hallucinogenic.

Amitriptyline because I am already on another antidepressant Lexapro for anxiety. Plus I took a cousin Imipramine (it's cousin) years ago and it turned me into a zombie and all I did was sleep on it.
Also worried about taking 2 antidepressants together can cause Serotonin Syndrome.

Clonidine I also took in the past and made my blood pressure really low. I got faint upon standing up too quickly.

My first experience with a compounded rx. How much of these drugs actually get into the bloodstream when taken topically.

Sorry...just a bit nervous. Thanks for listening!