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Old 10-11-2017, 11:08 AM
Hains Hains is offline
Junior Member
 
Join Date: Jul 2016
Posts: 58
5 yr Member
Hains Hains is offline
Junior Member
 
Join Date: Jul 2016
Posts: 58
5 yr Member
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Quote:
Originally Posted by kiwi33 View Post
A PubMed search for "ketogenic diet" returns 2118 papers.

A search for "ketogenic diet" and "traumatic brain injury" returns 12 papers.

None of these 12 papers provide clinical evidence that a ketogenic diet is of benefit to people with TBI.

NT members may draw their own conclusions from this.
Actually kiwi33, your statement is misleading and untrue.

Firstly, I reproduced your PubMed search using the same search terms you've mentioned above.

One of my search hits was a study by Greco et al titled Ketogenic diet decreases oxidative stress and improves mitochondrial respiratory complex activity. This study concluded with the following statement:
"These results strongly suggest that ketones improve post-TBI cerebral metabolism by providing alternative substrates and through antioxidant properties, preventing oxidative stress-mediated mitochondrial dysfunction."

Ketogenic diet decreases oxidative stress and improves mitochondrial respiratory complex activity. - PubMed - NCBI

Secondly, a search with the terms "ketogenic diet" AND "concussion" found an article by Prins and Matsumoto (2014) titled The collective therapeutic potential of cerebral ketone metabolism in traumatic brain injury. This study concluded the following:
"Preclinical studies employing both pre- and postinjury implementation of the ketogenic diet have demonstrated improved structural and functional outcome in traumatic brain injury (TBI) models, mild TBI/concussion models, and spinal cord injury."

Thematic Review Series: Calorie Restriction and Ketogenic Diets: The collective therapeutic potential of cerebral ketone metabolism in traumatic brain injury


kiwi33, I hope you understand that that people on this form struggle for extended periods of time with PCS as the science is just starting to come out of the dark ages of brain and concussion research. This is evident to everybody who has gone to the doctors office for a concussion and gone home with a useless prescription and no real solutions. Up until the last few years people with brain injuries were dismissed with psychological issues because of naivety and ignorance in the medical community. There is no magical pill or one-off solution to PCS. Many people suffer for years and years with little hope and no good ideas for recovery. It is critically important that we explore options like ketosis, promising new sciences that could offer relief to people who struggle endlessly. Your statement does not support such progress and you offer no alternative solutions, you're just putting up brick walls **

Not every idea is backed by double blind gold standard studies which take years to complete and cost millions of dollars. These types of clinical studies are often only affordable to big pharmaceutical companies who have no interest in suggesting that people change their diet. They want people to be hooked on pills, the evidence is clear. I've seen you chime in on a few different threads for different PCS topics, always with the same negative theme. You should be careful with your statements as they cause one to question your ethics.

Hains

Last edited by Jomar; 10-11-2017 at 11:13 PM. Reason: ** per guidelines
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