Hi all. I am refractory too and just had 3 of 4 infusions of Rituxan. makes me really sick for a couple of days, but I am feeling serious relief from my symptoms.

I have had MG for at least 25 years, and was actually treated for Lyme disease at one point.

Finally, a neurologist found a 2.2 pound thymoma crushing my left lung and laying against my heart. I felt pretty bad all the time. After the surgery though, everything went to hell and my condition became severely worse over the next several months. It's been a slow battle of ineffective drugs, but this Rituxan seems to be working for now. I just don't know how long it will last.

Good luck to all of you!