Hi, Elaine - I have MGUS-related PN which is progressive. Not sure whether CDB oil will help you, but I have found useful an edible product (chocolate truffle form) that contains 10mg CBD and 10mg THC. THC works synergistically with CDB, making it more effective. There are products with lower levels of THC that will also work, but I like the high, so these truffles are my "go to" for pain at night. I usually eat one a couple hours before I tuck in for the night if am having any foot/toe/ankle pain. The product does have a euphoric effect from the THC, which also helps my mood - I'm sometimes actually cheerful! The product takes a couple hours to kick in, but definitely "quiets" my nerves and brain, allowing me to sleep. Best of luck with the oil. Let us know if it works for you.