If I have my facts straight (which is questionable) I am under the impression that when alcohol is ingested it affects the brain first (the neurons) and thus, over time, the abuse of the pathway between the neurons (neurotransmitters) has an affect on the entire nervous system. The nerve endings (feet and hands) probably take the brunt of this damage and therefore we have PN.
I am not a fan of running, but if I can jog, snow ski and dance again I will be more than happy