Geneo76, I've been working with and taking grape seed extract since 1995. I'm still learning about it. I can't tell you yes or no, but it does WORK on our CIRCULATION.

You can do some searches on this and grape seed ex and it does work on veneous insufficiency. As long as you are not taking a pharma blood thinner there should be no problem taking it. If it were me, I'd start with 300mg and get to a couple times per day. Sometimes maybe 600mg at a time. Loading dose is the high dosing.

Again, I'm not a doctor but been using grape seed ex for going on 23 yrs.

Wish you the best and I'm here if you have more questions.