Senior Member
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Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,059
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Senior Member
Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,059
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proudest_mama,
What was your regimen (times, dose, drug/food) both before and after the change?
I'd check that the conversion was done correctly. The levodopa equivalent dose of 1mg pramipexole/Mirapexin is 100mg.
As Jo*mar says, I'd check on protein in the diet and gastric emptying.
I'd also note that pramipexole has a longer half-life than LC (600 min cf 90 min). This means that a reduction in pramipexole with an equivalent increase in LC will likely leave you more "off" in the morning.
John
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Born 1955. Diagnosed PD 2005.
Meds 2010-Nov 2016: Stalevo(75 mg) x 4, ropinirole xl 16 mg, rasagiline 1 mg
Current meds: Stalevo(75 mg) x 5, ropinirole xl 8 mg, rasagiline 1 mg
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