Touching on the heartburn issue..
Sometimes it can be that your stomach is not producing enough stomach acid.. and the meds make that situation worse..
Things get backed up because digestion is slowed...

Some information.. and tips -
16 Warning Signs Of Poor Digestion That Everyone Ignores! - Butter Nutrition
Digestive problems: Why does digestion slow down when we age?
14 Home Remedies for Heartburn and Acid Reflux

more-
slow digestion home remedies - Google Search