Hey, thanks for the messages. Apologies for the late reply, I thought I had e-mail notifcations setup but must have not saved the settings.

Thanks for the link Kiwi33; that's intereting to read and not a paper I had seen. Fortunately I have access to academic papers so have had a quick scan through. It certainly seems that the sensitivity of my reaction was atypical given the dosage. Though it shows there certainly are similar cases;
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*I had to remove the 'www' As I haven't posted before (hope in this instance it is OK).

I imagine my sensitivty to this medication is likely why I now have permanent neuropathy (though much improved).

I have wondered whether being a frequent renal stone former could be a risk factor for the SPN reaction, given the majority of renal stones are caused by issues/differences in absorption in the gut. Perhaps in someway it might affect absoprtion rates of certain drugs. Though likely a bit of a stretch!

Thanks again for the link.