I was diagnosed last year with anti-mag and WM. I go to the Mayo Clinic and have had 2 rounds of Rituxin to treat my anti-mag symptoms. In addition to PN, it has caused high blood pressure and digestive problems as a result of mylen degeneration of nerves and muscles to vital organs. Rituxan therapy has been very good at reducing my numbers and symptoms but not long lasting. I am hopeful of some new targeted therapies in the future that will be more effective so I don't have to take Ibrutinib. Trying to put that off as long as possible. It took 12 years for someone to finally diagnose me. Very frustrating! But now I have great doctors at Mayo!