He put me on 30 mg of cymbalta to start and 1/2 the dose of zoloft and I am sure about wellbutrin but I told him they didn't work. He tried to me into upping the zoloft and I said I don't think it would work. he said the cymbalta could affect my blood pressure. i am on pills for high blood pressure so I don't know if that will counteract the effect. i don't think the 30 will help.