Thanks Marlene. I don’t think I did a good job of explaining myself or asking my questions.

I have trouble absorbing b12 and folate for no known reason.

I’ve been taking 1000mcg b12 with 400mcg folate and 1.5 b6 for a couple of months.

I felt really good, less tired, less neuropathy symptoms and less depressed for about two weeks. That was six weeks ago. I’ve continued on the same dose, but all of the old symptoms are back and it’s as though I’m not taking anything. I was curious if anyone has had that happen and if so, wondering if a higher dose helped.

Also, do people here that supplement with 1000mcg or 5000mcg b12 take it alone or do you take it along with folate and b6? I’ve read that without the folate and b6, the b12 just ends up being peed out.