wendy s said:

"They suggested continuing without the motor assist, staying down at 80 to 90 rpm, keeping my heart rate up by increasing the resistance, and cycling every second day."

When Dr. Alberts' office said to keep your heart rate "up", I presume they meant up above 60% of HRmax, as per their original protocol.

Given the results of the SPARX trial, and the preliminary results of the CYCLE trial, I am now keeping my heart rate in the range 80 to 85 percent of HRmax.

I'll look at this again when/if the full results of the CYCLE trial are finally published.