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Old 02-07-2019, 04:48 PM
johnt johnt is offline
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Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,059
15 yr Member
johnt johnt is offline
Senior Member
 
Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,059
15 yr Member
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I am not a doctor, so make of this what you will.

You mention dystonia several times, but not dyskinesia, this suggests to me that you should discuss with your doctor an increase of medication.

Rather than make a change to the whole daily drug regimen, I think it would be best to take it one step at a time: focus on the worst symptom make a small change, assess, and if not successful go back to where you started.

You might be interested in plotting your levodopa equivalent plasma levels during the day and mapping them to your symptoms. See:

Parkinson's Disease Measurement: PwP, surveys, trials, analysis

This app uses a pharmacokinetic approach (CMAX, TMAX, THALF) to add together different doses, drugs and timings to get a net figure for each minute of the day. For instance, roughly speaking 75mg Stalevo (L/C/E) has the same impact as 100mg L/C.

John
__________________
Born 1955. Diagnosed PD 2005.
Meds 2010-Nov 2016: Stalevo(75 mg) x 4, ropinirole xl 16 mg, rasagiline 1 mg
Current meds: Stalevo(75 mg) x 5, ropinirole xl 8 mg, rasagiline 1 mg
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