Side Note to Frogga -

You speak of RSD induced osteoporosis. I've also heard you mention bone crushing pain.

I don't know if you tried it, but I've had about a 50% reduction on my deep bone pain following infusions of Zometa (zoledronic acid), which is in the pamidromate family, a class of drugs designed to inhibit the uptake of bone tissue into the blood stream in patients with multiple myeloma. (I thought that would get your attention.)

According to my pain dr. - a prof. at a local medical school - they don't have a clue as to it's mechanism in treating RSD, all they know is that it works. I may have mentioned this article before, but it's definitely worth checking out: "Efficacy of Pamidronate in Complex Regional Pain Syndrome Type I," Robinson JN, Sandorn J, Chapman PT, Pain Medicine. 2004; 5: 276-280, a copy of which is attached. See also, the attached copy of "Pharmacologic Therapies for Complex Regional Pain Syndrome," Mackey S and Feinberg S, Current Pain and Headache Reports, 2007; 11: 38-43, and in particulr the discussion under "Bisphosphonates."

I personally didn't gain any relief after my first infusion, but after the third in three months, things got much better. The only downside is that you can't need or anticipate having any major dental work done while you're on the stuff, e.g., root canals, where it's been linked to jaw necrosis.

I would definitely have that one checked out.

be well,
Mike

Attached Files

	Efficacy of Pamidronate in Complex Regional Pain Syndrome Type 1 - Robinson.pdf (90.5 KB, 77 views)
	Pharmacologic Therapies for CRPS Mackey and Feinberg - 2007.pdf (114.4 KB, 127 views)