Hi Atticus, I'm sorry you have this dx. For me, and I have large fiber/axonal though, it's 24/7. What kind of symptoms do you have? If it's off and on, that may be good sign that something you're doing is activating it. You may be able to figure that out. Scan the board, use the search function and you'll likely get some ideas to try, like activities/diet/supplements etc. You might also consider a 2nd or 3rd opinion, doctors vary quite a bit in experience and motivation to help folks with this disease. Good luck!