Originally Posted by Lonestar

Hey Atticus,

I can definitely relate to the stress component of this, and I think most folks on this forum can too. Even though my nerve symptoms have (thankfully!) always been pretty mild compared to most of the PN stories I've encountered (i.e. they've never really interfered with my daily life beyond being an annoyance), the uncertainty as to the cause of my symptoms and the possibility of my neuropathy getting much worse has been a big point of concern for me.

For me, time, lots of research, and some improvement after starting thyroid treatment have really helped to ease my stress about my nerves. Like you mentioned above, stress definitely exacerbates my symptoms too, so things tend to compound in either direction - stress leads to more symptoms, which leads to more stress, and vice-versa.

It sounds like you're doing everything you can to diagnose/treat your PN and that you've largely ruled out the standard metabolic stuff including thyroid.

One question though: do you have the actual TSH/T3/T4 numbers from your blood test?

The only reason I ask is that "normal" TSH is a bit of medical gray area. I recall reading a study that suggested anything over about 2.5 pg/mL is higher than ~90% of the population. Many doctors won't consider treating thyroid disorders until either T3/T4 is off or TSH is consistently over 10 pg/mL. If you're on the high end of the normal range (TSH>3.0 pg/mL), thyroid could still be a factor. For reference, my TSH was typically around 6-8 pg/mL for years. Until my nerves started going haywire, I was basically asymptomatic, and to this day I have had no other symptoms consistent with thyroid problems except slightly elevated (though still "normal") cholesterol (i.e. normal weight, not lethargic, no hair falling out etc.).

Good luck going forward.

L