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Old 05-04-2019, 09:43 AM
Tupelo3 Tupelo3 is offline
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Join Date: Mar 2013
Location: New Jersey
Posts: 832
10 yr Member
Tupelo3 Tupelo3 is offline
Member
 
Join Date: Mar 2013
Location: New Jersey
Posts: 832
10 yr Member
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Another one bites the dust....




Quote:
Originally Posted by johnt View Post
5 years later ...

.
My thanks go to Iqbaliqbal at HU for alerting me to this.

The STEADY-PD III trial:

Blood pressure drug shows no benefit in Parkinson's disease -- ScienceDaily

"The phase 3 study involved 336 people with early Parkinson's disease at 54 sites in the US and Canada as part of the Parkinson Study Group. Half of the participants received 10 milligrams daily of isradipine for three years, while the other half received a placebo."

Calcium Channel Blocker Flops in Parkinson's Disease Trial | Medpage Today

"No significant difference was seen after 36 months in average Unified Parkinson Disease Rating Scale (UPDRS) Part I-III scores measured in the ON state for patients receiving isradipine (DynaCirc) at 10 mg daily versus placebo (treatment effect 0.27 points, 95% CL -2.5 to 3.0, P=0.85)"

John
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