Thread: Suspected PN
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Old 05-28-2019, 11:46 AM
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Chemar Chemar is offline
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Quote:
Originally Posted by gert View Post
it says in that report
alpha lipoic acid, offers little benefit
That's not what I see in the report, gert?

Quote:
Alpha lipoic acid: The benefit provided by alpha lipoic acid (ALA) in the treatment of DNP possibly is due to its direct effects on the neuropathy, by reducing the oxidative stress, which has been defined as an important factor in the physiopatology of the diabetic neuropathy[122]. Its antioxidant and anti-inflammatory actions may contribute to an all-round improvement of diabetic neuropathy symptoms[135]. In some clinical trials that evaluated ALA effect in diabetic patients, pain was not a primary end point. However, they have shown a moderate benefit in terms of pain reduction[132]. In a randomized double-blinded trial, ALA-treated patients reported a greater reduction in neuropathic pain when compared to placebo-treated subjects[122]. Compared to several drugs currently in use for DNP treatment, ALA has fewer side effects[30], being nausea and vomiting the most common[132].
The quote I posted is from the link kiwi provided you. Diabetic neuropathic pain: Physiopathology and treatment
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