Thread: PET imaging of serotonin system reveals PD many years before motor symptoms appear
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Old 07-01-2019, 03:24 AM
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kiwi33 kiwi33 is offline
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Join Date: Jan 2015
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8 yr Member
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The aldehyde form of serotonin promotes formation of alpha-synuclein oligomers and serotonin blocks formation of amyloid from alpha-synuclein.

Whether these are clinically relevant remains to be seen.

The serotonin aldehyde, 5-HIAL, oligomerizes alpha-synuclein. - PubMed - NCBI

The neurotransmitter serotonin interrupts α-synuclein amyloid maturation. - PubMed - NCBI
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