First, thank you for actually taking the time to read and address my issue MH - I'm super grateful for any attention people give to my situation.

- I tend to agree with you that it fit the description of sort of neuropathic process more than some sort of functional neurological disorder (though I can't rule that out completely either) since it def progressing in a sock and glove fashion. I've seen a few neurologists who seem somewhat uninterested in finding a cause and are content at just calling it "idiopathic" and treating it with lyrica/ gabapentin.. their rationale being that the treatment would be the same... but if it is something like you mentioned below than it makes sense that supplements/ etc could at least partially address the issue and slow progression maybe? I don't know.

Do you mind if I ask you you discovered your low serine levels as a cause? -- did you simply stumble across it on the internet? Did your tests come back with low serine levels (I don't know if I've even been tested for that - will check my bloodwork). Can you pass on any links/ articles that may address it?

"They are finding out interesting things like elevated folate levels or low serine levels are associated with neuropathy that weren't covered in medical school for these neurologists. I did just that and found that I had abnormally low serine levels that were likely contributing to the production of neurotoxic deoxysphingolipids. I now supplement with L-serine and use oxybutynin and have seen some positive changes in my neuropathy.

-How long after supplementing with L-Serine and oxybutynin did you experience any difference?