I have been supplementing with MSM powder for many years. 2 tps daily for sure. 1 tsp with 8 oz spring water in morning, one about later afternoon say way. Many take capsules but I prefer to use the power here and it does help with pain, dulls it. I live with advanced OA for about 60 yrs....and it advanced over the years...started at 18 and I'm 81.

https://draxe.com/nutrition/msm-supplement/

On the gluocosamine, I take 2 capsules of Cosamin DS daily, dosage calls for 3 but I take 2. A dear friend who died at 95, walked to the end and believes this supplement kept her moving. She was a marvel..