I have been on Soliris for 15 months. Initially the change was very dramatic, but that may have been due to both the loading dose (every week) and the residual effects from weekly IVIG. At the beginning I was also taking CellCept (2g/day) and prednisone (30mg/day). After three months I was functioning well enough to start reducing my predinisone.

I am now down to 2.5mg/day of prednisone. I've been on that dose for 2 months but will probably need to increase it a bit since I've become weaker.