Well i’m very late on this one.

It may actually be the other way around. I read a study some time ago done on rats where they tested out many different things.

One of the things they did was give male rats high doses of estrogen before inducing a concussion in the them. They then noted behaviour and mortality rates. The male rats that had been giving estrogen recovered faster and the mortality rates were lower.

They theorised that estrogen may have neuroprotective/ anti inflamatory properties.

The weird things is when they gave the female rats estrogen it worsened their recovery times, and increased the mortality rate.

Maybe estrogen is good up to a certain level, where it becomes too much and then counter productive?

Ofcourse rats and humans are different, so it may be completely non applyable but still interresting.